Asian Journal Of Social Pharmacy

Abstract: Objective To identify the core technical topics and innovative development paths in the field of genetically engineered vaccines, study the potential technological development opportunities, and to provide suggestions for enterprises and the government to plan strategically and gain advantage in a highly competitive market. Methods Based on patent information, patent analysis was carried out from three aspects: technological innovation trend, life cycle, and technical layout, and the development status of the field was summarized. Then, the topic model was used to mine the important technical topics. Finally, the subject-action-object (SAO) structural chain was extracted to construct and visualize the development path of technological innovation. Results and Conclusion Genetically engineered vaccines are in the growth stage with great development potential. The innovative development paths of three technical themes include four aspects: Immune response, immune adjuvant, humanized transformation, carrier and delivery. In this regard, the government should actively make overall planning and scientific guidance to improve the efficiency of technological innovation and promote the long-term development of the industry.

Key words: genetically engineered vaccine, patent analysis, innovative development