Asian Journal Of Social Pharmacy

Objective To improve the system of accelerated review and approval, and to speed up the development and marketing of repurposing drugs for rare diseases in China. Methods The relevant concepts of rare diseases and the definition of drug repurposing were introduced so as to sort out the advantages and disadvantages of the research and development of drug repurposing for rare diseases. Then, the incentive mechanisms of the research and development of drug repurposing for rare diseases in China and abroad were compared. Results and Conclusion Some suggestions on improving the incentive mechanism of repurposing drugs for rare diseases such as policy support for talents introduction, capital investment, and innovation capabilities are proposed. Besides, the government should further improve policies for the research and development of repurposing drugs for rare diseases, which can gradually narrow the gap between the research and innovation of drug repurposing in developed countries, thus benefiting the patients of rare diseases.

rare disease, drug repurposing, incentive mechanism, innovation ability