亚洲社会药学

本期目录

2024年, 第19卷, 第2期　刊出日期：2024-06-20 上一期    下一期

Select

Improving the Selection Model of Essential Medicines in China by Evidence-based Thinking Sun Huanzheng, Fan Jianing, Dong Li, Sun Lihua 2024 (2):  99-105.  摘要 ( 87 )   PDF(789KB) ( 304 )   Objective To sort out the problems in the selection model of essential medicines in China, and to put forward some suggestions to optimize the selection model to ensure the rationality of the medicines in the essential medicines list. Methods The domestic and foreign literature on the selection of essential medicines was reviewed. Then, the opinions on the selection methods and results of essential medicines from foreign literature were investigated to make a comparison with the selection of essential medicines in China. Finally, the general and special laws of the selection process of the essential medicines were explored. Results and Conclusion It is recommended that the selection model of essential medicines in China should be further optimized, and the evidence-based thinking and methods should be utilized to enhance the scientific nature of the selection process. 相关文章 | 计量指标

Select

Research on Construction of Pharmacovigilance System for Marketing Authorization Holders in China Zhao Jiali, Tian Lijuan 2024 (2):  106-116.  摘要 ( 102 )   PDF(885KB) ( 155 )   Objective To provide suggestions for helping marketing authorization holders (MAHs) to develop an effective and compliant pharmacovigilance system. Methods The construction strategies of pharmacovigilance system of the multinational pharmaceutical companies were analyzed based on the requirements of regulations and laws. Results and Conclusion There are some gaps between local and multinational pharmaceutical companies in the construction of pharmacovigilance system. We can learn from the experience of multinational pharmaceutical companies to improve the pharmacovigilance system, which includes building a sound pharmacovigilance organizational structure, establishing a series of operational system files and cultivating professional talents. MAHs of China should improve the structure of enterprise pharmacovigilance system. Besides, members of Drug Safety Committee should be department managers with higher position so that they can fulfil the responsibilities of risk assessment. If MAHs possess a large variety and quantity of products, a Drug Safety Committee should be established to ensure the timely discovery of risks. In addition, MAHs should pay attention to the implementation of related regulations and laws on pharmacovigilance and establish compliant, effective and operatable files combing with the actual operation of pharmacovigilance system. Finally, MAHs should introduce and train pharmacovigilance talents, and hire pharmacovigilance experts as consultants to solve the problem of talent shortage. 相关文章 | 计量指标

Select

Analysis of Drug Medical Insurance Access Pricing Based on the Perspective of Binary Equilibrium Zhang Junjun, Wang Shuling 2024 (2):  117-125.  摘要 ( 79 )   PDF(882KB) ( 64 )   Objective To study the influencing factors in the process of national medical insurance negotiation and drug pricing from the dualistic equilibrium perspective, and to provide reference for the harmonious management of drug pricing in China. Methods Through the literature analysis and policy review, the pricing subject, pricing basis and price control system in the pricing process of medical-accessed medicines were analyzed from the perspective of binary equilibrium and harmonious management. Results and Conclusion It is found that four balances in the drug pricing process, two balances in pricing basis and three balances in price control system need to be considered, respectively. Drug pricing is the key content of national medical insurance access, which is also the hotspot of the policy in the pharmaceutical fields in recent years. Drug pricing not only reflects the value of drugs, but also reflects a lot of top-level designs of binary equilibriums in medical insurance policy. While the rational design of drug pricing requires the joint efforts of the government, pharmaceutical companies and relevant experts to comprehensively consider many equilibriums, so as to improve the relevant systems. 相关文章 | 计量指标

Select

Identifying and Managing Technical Risks in the Process of Innovative Drugs Development in China Diao Yuanyuan, Wu Zhiang 2024 (2):  126-134.  摘要 ( 71 )   PDF(800KB) ( 44 )   Objective To identify technical risks in the process of innovative drug development, and to provide reference for technical risk management so as to reduce the uncertainties and improve the efficiency of research and development. Methods The initial risk index was investigated by literature research. Then, the Likert scale was used to design a questionnaire, and the experts’ opinion was used to analyze the risk factors affecting the different stages of the development of innovative drugs in China. Results and Conclusion Based on the analysis of questionnaire, 31 risk indicators of five key stages in the development of innovative drugs from drug discovery to marketing authorization were established. The key risk indicators constructed in this study can provide reference for technology-related risk management in the process of innovative drug development. 相关文章 | 计量指标

Select

Research on the Threshold Effect of China’s Pharmaceutical Export Trade on Internal and External R&D Investment Qiao Jiahui, Song Yu, Gong Jingran, Chen Yuwen 2024 (2):  135-146.  摘要 ( 84 )   PDF(2118KB) ( 73 )   Objective To study the threshold effect of export trade on internal and external R&D investment in China’s pharmaceutical industry, and to provide reference for some pharmaceutical enterprises to improve the investment. Methods The panel data of pharmaceutical industry in 25 provinces and cities in China from 2009 to 2019 were selected to conduct empirical analysis by establishing a threshold regression model, and a better export trade interval was obtained. Results and Conclusion There is a threshold value for the effect of new product export on both internal and external R&D expenditures, and the threshold values are 845.278 8 million yuan and 318.419 8 million yuan, respectively. There is a single threshold effect of export trade on both internal and external R&D investment in China’s pharmaceutical industry, and the effect of export trade on internal and external R&D investment changes from negative to positive as the export trade develops from low to high. 相关文章 | 计量指标

Select

Game Analysis of Regulation for Online Prescription Drugs under Customer Feedback Mechanism Du Peng, Huang Zhe, Dong Li 2024 (2):  147-158.  摘要 ( 63 )   PDF(21056KB) ( 35 )   Objective To study the way to better regulate the online sales of prescription drugs, and to provide reference for the adjustment of relevant policies since the online sales of prescription drugs has become an inevitable trend. Methods A game model was constructed for the strategy choice of pharmaceutical e-commerce platform, customers and government departments based on differential game theory and Nash equilibrium game model to analyze the pure strategy Nash equilibrium, Nash equilibrium dominant strategy of each subject and the mixed strategy Nash equilibrium under different conditions. Besides, Matlab was used to carry out simulation analysis. Results and Conclusion The study shows that: (1) Improving the credibility of the government and reducing the cost of government regulation can not only make the pharmaceutical e-commerce platform operate with high quality, but also give greater play to government functions; (2) The greater the influence of social evaluation on pharmaceutical e-commerce platforms, the lower the cost of high-quality operation of pharmaceutical e-commerce platform, and the greater the probability of customer choosing real evaluation strategy; (3) The greater the customers’ perception of potential risk, the greater the compensation, and the lower the cost of reporting. Then, the greater the probability that government departments will choose strict regulation. Finally, the model solution and simulation analysis are combined to provide countermeasures and suggestions for the safety regulation of online sales of prescription drugs. 相关文章 | 计量指标

Select

Digital Transformation Trend of the Pharmaceutical Distribution Industry in the Context of New Infrastructure in China Gan Xingzhi 2024 (2):  159-167.  摘要 ( 73 )   PDF(1533KB) ( 89 )   Objective To study the pharmaceutical distribution industry against the background of new infrastructure construction since it is vital to the health and life of the public, and to offer some suggestions to further improve the industry quality and achieve industry upgrading. Methods The national strategies for new infrastructure as well as the underlying logic for enterprise digital transformation were analyzed to provide the outlook on the digital transformation trend of the pharmaceutical distribution industry. Results and Conclusion In the future, the pharmaceutical distribution industry shall transform the pattern, channel, management and control, and experience in the entire business chain in a digital way by focusing on connection efficiency, data efficiency and decisionmaking efficiency. 相关文章 | 计量指标

Select

Comparison of the Development Model of DTP Pharmacy between China and the United States and Its Enlightenment Li Yanli, Huang Zhe 2024 (2):  168-177.  摘要 ( 106 )   PDF(940KB) ( 141 )   Objective To systematically analyze the development status of DTP pharmacy in the United States and China, and to find out the problems in China’s DTP pharmacy and put forward some countermeasures and suggestions. Methods Relevant literature was searched and reviewed to study the history, market scale and development trend of DTP pharmacy in the United States and China. Then, the problems in China’s DTP pharmacy were found out. Results and Conclusion DTP pharmacy model in the U.S. has taken shape and is maturing. The high degree of industry concentration is an important feature of the U.S. pharmacy. In contrast, China’s DTP pharmacy started late, and the industry pattern has not yet been finalized. There are still some problems in the DTP pharmacy certification and quality management. It is recommended to promote the rapid development of DTP pharmacies in China by encouraging the outflow of prescription drugs, establishing a third-party pharmacy accreditation organization and strengthening the team of licensed pharmacists and other personnel. 相关文章 | 计量指标

Select

Study on the Changes of Medical Income Structure in Government-run Hospitals of Traditional Chinese Medicine from 2012 to 2021 Song Yamei 2024 (2):  178-190.  摘要 ( 73 )   PDF(906KB) ( 63 )   Objective To study the changing characteristics and trend of medical income structure in the governmentrun hospitals of traditional Chinese medicine (TCM), evaluate the effects of relevant reform measures, and to put forward corresponding suggestions for further optimizing their income structure. Methods The data related to the average medical income of government-run hospitals of TCM from 2012 to 2021 were sorted out. Then, descriptive analysis method was used to analyze the changes of related indicators. Besides, structural change method was applied to investigate the changes of outpatient income and inpatient income. Results and Conclusion From 2012 to 2021, the growth of medical income in government-run hospitals of TCM tended to be stable, and the proportion of medical service income increased from 22.62% (2012) to 29.38% (2021), but the average annual growth rate was only 0.68%. The main items that caused the change of outpatient income structure were medicine revenue, laboratory tests, diagnosis and treatment, and the cumulative contribution rate was 89.15%. The main items that caused the change of inpatient income structure were medicine revenue, sanitary materials, and auxiliary examinations income, with a cumulative contribution rate of 80.04%. However, the contribution rate of registration, diagnosis, treatment, surgery and nursing income reflecting the value of medical personnel’s technical labor was relatively small. The medical income structure of government-run hospitals of TCM underwent great changes and gradually became reasonable, but the medical service income increased slowly, and not all indicators achieved the expectations. To promote the sustainable development of public hospitals of TCM and enable them to provide high-quality and efficient TCM medical and health services, it is necessary to further improve the relevant policy mechanism. 相关文章 | 计量指标

Select

Analysis of Technical Intelligence of Tumor Cell Therapy Based on Patent Map Liu Yue, Zeng Yingying, Li Xue, Yuan Hongmei 2024 (2):  191-201.  摘要 ( 75 )   PDF(4740KB) ( 40 )   Objective To analyze the technical information in the field of tumor cell therapy in China, and to provide reference for identifying technical trends and predicting technical opportunities. Methods Based on the patent data in the field of tumor cell therapy in China, the patent map method was used to construct a scientific technical information analysis model. Then, the technical status of new drug research and development in this field was explored to identify technical opportunities. Results and Conclusion Studies have found that China’s tumor immunotherapy is in the growth stage. The technical innovation regions are mainly distributed in the east and innovative entities are enterprises. Technology hotspots are concentrated in areas such as A61P35, C12N5, and the patented technical efficacy is high. Besides, the technical research and development opportunities identified are closely related to the background in this field. To better promote the development of the industry, enterprises and research institutions should strengthen cooperation in technological innovation Meanwhile, they should pay attention to technical efficacy analysis to identify more technical opportunities, thereby effectively guiding innovation strategic decisions. 相关文章 | 计量指标

Select

Countermeasures and Suggestions for Strengthening Human Resource Management in China’s Pharmaceutical Industry Sun Yuyuan, Wang Shuling 2024 (2):  202-207.  摘要 ( 73 )   PDF(868KB) ( 98 )   Objective To provide reference and enlightenment for the development of human resource management in China’s pharmaceutical industry and to put forward some suggestions to promote the further development of pharmaceutical industry. Methods The method of literature review was used to analyze the current situation and existing problems of human resource management in China’s pharmaceutical industry. Results and Conclusion Only by continuously improving the human resource management skills and innovating management methods can pharmaceutical enterprises achieve long-term benefits with sustainable development. The formulation of human resource management strategy in pharmaceutical industry must be conducive to the realization of the business goals of enterprises. To achieve this overall goal, the human resources management department of enterprises must make the plan from a strategic perspective, formulate talent strategic planning which serves the overall strategic goal of the enterprise. As a result, human resource management will play an important role in the development of China’s pharmaceutical industry. 相关文章 | 计量指标