亚洲社会药学

本期目录

2020年, 第15卷, 第1期　刊出日期：2020-03-20 上一期    下一期

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Factors Influencing the Implementation of Drug Standards Improvement in China Zhao Jianfeng, Zhang Wei, Yu Hai 2020 (1):  1-6.  摘要 ( 391 )   PDF(804KB) ( 405 )   Objective To explore the factors influencing the implementation of drug standards improvement in China, and to offer some suggestions for improving drug standards. Methods Factor analysis was used to investigate the influencing factors by referring to the literatures, experts’ interview and collecting data through questionnaire, and then data were analyzed by SPSS21.0 statistical software. Results and Conclusion The results showed that there were four factors that affecting the plan of the national drug standards improvement. They were mechanism factor, design factor, constraint factor and motivation factor. And corresponding management suggestions for improving the efficiency of the plan were put forward. 相关文章 | 计量指标

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Compulsory Licensing of Pharmaceutical Patents System from the Perspective of Public Interest-Public Health in China Zhang Yubo, Yuan Hongmei 2020 (1):  7-15.  摘要 ( 565 )   PDF(757KB) ( 440 )   Objective To study the types and acquisition paths of drug data in the administrative act of compulsory licensing of pharmaceutical patents so as to provide data support for the implementation of compulsory licensing of pharmaceutical patents from the perspective of public interest-public health in China. Methods Situation of compulsory licensing of pharmaceutical patents in the context of public interest-public health in China was selected, combined with international conventions and the principle provisions of relevant laws, and cases of compulsory licensing of pharmaceutical patents in foreign countries were reviewed to extract drug-related data of compulsory licensing of pharmaceutical patents. Results and Conclusion According to the analysis of China’s compulsory licensing of pharmaceutical patents theory and legal provisions, the data could be divided into five categories for compulsory licensing of pharmaceutical patents in China: diseases, drugs, patents, generic drug enterprises, and licensing fees. Although, some data are traceable. There were also problems in obtaining data or inconsistent standards in five levels of compulsory licensing of pharmaceutical patents in the context of public interest-public health. It was not conducive to the implementation of compulsory licensing of pharmaceutical patents in China. Thus, it should be further established a unified data support system at the national level, specifying the standard of licensing fee, implementing relevant laws and regulations. 相关文章 | 计量指标

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Application Research of Earned Value Management in New Drug Research and Development Projects Wang Wanting, Xing Hua 2020 (1):  16-21.  摘要 ( 432 )   PDF(732KB) ( 527 )   Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects. Methods Cost analysis and financial forecasting were carried out with the integrated approach of earned value management. According to the principle of earned value management deviation analysis, the basic process of the new drug research and development project was combined with the hypothesis method from the research of Tufts Drug Development Research Center. Results and Conclusion If the project progress check was carried out in the clinical trial, the project costs were found overspent, the efficiency was low, the project progress was faster, and the resource investment was ahead. It is recommended that the adjustment should be made to reduce the input of resources, and increase the efficient key personnel to take the place of some less efficient staff. 相关文章 | 计量指标

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Pharmacoeconomic Evaluation of Rituximab (Hanlikang) for Patients with Rheumatoid Arthritis Wang Yanqi, Chen Binbin, Zhao Mengmeng, Sun Lihua 2020 (1):  22-29.  摘要 ( 442 )   PDF(1014KB) ( 441 )   Objective To provide reference for clinical medication and drug policy formulation for patients with rheumatoid arthritis. Methods A Markov model was established for patients with moderate and severe rheumatoid arthritis. The model period was 6 months and the simulation time was the average life expectancy of Chinese residents (76 years). The cost-utility analysis method was used to analyze the effect of Hanlikang combined with methotrexate and Yisaipu combined with methotrexate from the perspective of the whole society. The economy of Hanlikang was evaluated and the robustness of the results was verified by sensitivity analysis. Results and Conclusion For the patients with moderate and severe rheumatoid arthritis, compared with Yisaipu, Hanlikang could save 69 228 yuan and gain 0.837 quality adjusted of life years (QALYs) in the whole life cycle with great economic advantages. The results of sensitivity analysis were consistent with those of basic analysis, and the results of probability sensitivity analysis showed that when the willingness to pay was the per capita GDP (64 644 yuan), the economic probability of Hanlikang group reached 79.3%. 相关文章 | 计量指标

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Research on the Transformation of Mapping Method for Cancer Patients’ Health Utility in the Asia-Pacific Region Zhang Jie, Sun Quan, Zhang Fang 2020 (1):  30-36.  摘要 ( 456 )   PDF(1007KB) ( 407 )   Objective To systematically collect the mapping functions of health utility values of various cancer patients in the Asia-Pacific region to provide scientific reference for domestic research in the field of cancer patients’ health utility values. Methods A systematic literature search was conducted by using PubMed, ScienceDirect, Web of Science, CNKI, VIP Database and Wanfang Database to collect studies on the application of mapping method for health utility value measurement from 2008 to 2019. The key words included cancer, scale, mapping, and health utility. The inclusion criteria for the studies were: (1) The research papers came from countries in Asia Pacific region; (2) Original research articles; (3) Written/published in Chinese and English. Results and Conclusion A total of 137 Chinese and English articles were retrieved, and 9 articles met the requirements in the screening. The literature was classified by the following types: (1) It had a clear functional relationship; (2) It had no clear functional relationship. Due to the small numbers of samples, the reliability of the research results is not high. The construction of mapping model should build multiple regression models to test the performance of the model combined with different index variables. In addition, due to the limitations of the research objects selected in the literature, more attention should be paid to the mapping function of other types of cancers. At the same time, the research and development of the original data should be focused on as well. 相关文章 | 计量指标

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The Analysis of Marketing Strategy of Plendil Fu Geyang, Tian Lijuan 2020 (1):  37-43.  摘要 ( 606 )   PDF(749KB) ( 916 )   Objective To provide marketing strategies suitable for the characteristics of the Chinese market by determining the strengths, weaknesses, opportunities and challenges of Plendil through SWOT analysis. Methods SWOT analysis of Plendil shows that the product is well-known with safety, tolerance, excellent performance, and good brand image. In addition, great market potential, and the gradual improvement of the medical market and the health insurance system all provide an exciting opportunity for its development. However, weaknesses and threats still exist, including unsound marketing policy and remuneration incentive system, poor channel control, fierce market competition, competition from foreign companies and domestic generic drugs, and the intensified state supervision efforts. Accordingly, our company shall speed up the design of marketing portfolio strategy through 4P theory. Results and Conclusion Establish brand image and ensure high quality products are conducive to maintaining advantages; Improve sales cost policy and salary incentive system, and strengthen channel control are conducive to overcoming disadvantages; Actively carrying out academic promotion is conducive to seizing opportunities; Accelerating product upgrading, formulating reasonable pricing strategies and developing relationship marketing are conducive to the company to cope with threats and maintain an advantageous position in the fierce market competition. 相关文章 | 计量指标

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Comparative Study on the Development of Urban Basic Medical Insurance in 14 Cities of Liaoning Province Zhi Yuanyuan, Wang Shuling 2020 (1):  44-56.  摘要 ( 428 )   PDF(1963KB) ( 421 )   Objective To put forward some suggestions for the development of urban basic medical insurance of Liaoning by comparing the development situations in 14 cities of Liaoning Province. Methods Relevant data of urban basic medical insurance from 2008 to 2018 in 14 cities were collected to make a comparative analysis, and the 5 why analysis chart was drawn to investigate the development differences in 14 cities. Results and Conclusion The average growth rate of the number of urban residents covered by urban basic medical insurance varied greatly from 2014 to 2018. The range of average growth rate of urban residents’ medical insurance is 19.1%, and the range of average growth rate of urban workers’ medical insurance is 9.1%. Funding standards are basically the same. It is suggested each municipal government should attach importance to this issue. They can make full use of information technology to coordinate with various authorities and ensure the smooth development of medical insurance. Besides, they must actively adapt to their conditions to better develop the urban basic medical insurance of Liaoning. 相关文章 | 计量指标