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本期目录

    2014年, 第9卷, 第2期 刊出日期:2014-06-20 上一期    下一期
    论文
    Analysis of Influential Factors on the Efficacy of Itraconazole Injection forTreating Fungal Infections in Hematologic Malignancies Patients
    DONG Wei-hua;;HUANG Tai-kang;;DONG Ya-lin;ZHOU Yang
    2014 (2):  47-50.  doi:
    摘要 ( 496 )  
    Objective To analyze the influential factors on the efficacy of itraconazole injection in the treatment of fungal infections for
    hematologic malignancies patients. Methods 85 hematologic malignancy patients with fungal infections were selected to treat with
    itraconazole injection. Multiple logistic regression was used to analyze 27 factors that probably affect the efficacy of itraconazole
    injection, these factors including four aspects: basic situation of the patients, use of itraconazole injection, combined drugs use, and
    laboratory indicators before and after treatment. Results and Conclusion Four factors such as the patient’s gender, the combination
    of fluconazole, macrolides, and carbamazepine were eventually conducted into the regression equation and we found the factors that
    reduce the efficacy of itraconazole injection were the combination use of fluconazole and carbamazepine.
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    Analysis of China’s Health Care Resource Allocation
    KONG Ling-da;LIU Ya-dan;WU Zhi-ang
    2014 (2):  51-55.  doi:
    摘要 ( 578 )  
    Objective To provide references for rational allocation of China’s health care resources. Methods Descriptive analysis and cluster
    statistics were conduced to analyze China’s health care resource allocation. Results and Conclusion Health care resource allocation
    is unreasonable to some degree and countermeasures are raised.
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    Chinese Herbal Medicine Exports: Existing Problems and Reflections
    ZHANG Zhi-dong;SUN Li-hua
    2014 (2):  56-59.  doi:
    摘要 ( 544 )  
    Objective To discuss the problems and reasons of the export situation of Chinese herbal medicines, and to provide suggestions for
    policy making. Methods Literature review was conducted to discuss the problems, such as resources pressure that Chinese herbal
    medicine export has brought about, technical trade barriers, and the low industry concentration of the export enterprises, etc. Results
    and Conclusion With the development of Chinese herbal medicine exports, China should perfect policies and regulations to protect
    the wild resources, formulate China’s export standards to deal with technical trade barriers, enhance the access threshold of export enterprises so as to enhance the competitiveness of the industry.
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    Biosimilars: Current Status and Countermeasures
    LI Yan-ru;TIAN Li-juan
    2014 (2):  60-63.  doi:
    摘要 ( 500 )  
    Objective To study the current status of biosimilars, and to explore strategies for the healthy development of biosimilars in China.
    Methods Literature review was conducted to summarize the status of biosimilars both at home and abroad. Results and Conclusion
    The development of biosimilars in China is not yet mature compared with the advanced countries. Support from both companies and
    the state is needed to promote the development of biosimilars in China.
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    China’s Marine Biopharmaceutical Industry:Existing Problems and Countermeasures
    ZHANG Li-jun;HUANG Tai-kang;
    2014 (2):  64-67.  doi:
    摘要 ( 551 )  
    Objective To explore the problems faced by marine biopharmaceutical industry in China and to put forward countermeasures.
    Methods Literature review was conducted and the problems faced by China’s marine biopharmaceutical industry were analyzed from
    the perspectives of scale, technology, financing, management and distribution. Accordingly, countermeasures were raised. Results
    and Conclusion Marine biopharmaceutical industry is the strategic emerging industry. The existing problems in the development
    of marine biopharmaceutical industry in china will be solved through strengthening overall coordination, promoting management
    innovation, consolidating science and technology, fostering industrial cluster and increasing capital investment.
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    The Comparison of IND Review Mechanismbetween China and the United States
    JIANG Chun-fei;YANG Yue
    2014 (2):  68-72.  doi:
    摘要 ( 503 )  
    Objective To study IND review mechanism between China and the United States, and to comment the advantages of review
    mechanism by FDA. Methods Literature review was conducted and official websites of drug regulatory authorities at home and
    abroad were searched to gain relevant information. Results and Conclusion IND registration management legal system in China is
    less perfect than that in the United States. IND review organization and procedures need to be further optimized.
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    Research of the Classification of Drug Risks
    YAN Quan;SHAO Rong
    2014 (2):  73-78.  doi:
    摘要 ( 547 )  
    Objective To classify drug risks according to the life cycle of drugs. Methods Case analysis was used to discuss the causes of drug
    injury events in the past decade, and to classify the drug risks. Results and Conclusion Drug risks can exist in four processes:
    drug research and development, manufacturing, management and drug use, which can be further detailed into 20 indicators. The
    classification of drug risks is scientific and rational, so it can help to allocate drug supervision resources rationally.
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    Marketing Channel Selectionsfor Different Biological Reagent Enterprises in China
    BAI Jian;;MIAO Lan-ying;LIN Da-yong;WANG Hai-bo;LI Ye
    2014 (2):  79-82.  doi:
    摘要 ( 591 )  
    Objective To probe into marketing channel selections for different biological reagent enterprises. Methods Influential factors on
    marketing channel selections for different biological reagent enterprises were discussed, and matrix model of product technical
    barriers-enterprise strength was built to study the causes and feasibilities of marketing channel selections for different biological
    reagent enterprises. Results and Conclusion It is suggested that the state-owned enterprises, foreign - invested enterprises, joint
    ventures should adopt directly- managed marketing channel, medium and small-sized enterprises adopt the agent marketing channel,
    patented the product- oriented enterprises adopt both the district agent marketing channel and the directly- managed marketing
    channel, and enterprises with low threshold technology adopt the multi-agent marketing channel.
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    Countermeasures to Reduce Economic Burden of the Schizophrenia in China
    DU Li-zhe;SUN Li-hua
    2014 (2):  83-86.  doi:
    摘要 ( 561 )  
    Objective To provide a theoretical reference and decision support for health care policy makers so as to reduce economic burden
    of the Schizophrenia. Methods Retrospective study was conducted to analyze measures to reduce the economic burden of the
    schizophrenia, and suggestions were raised based on learning experiences from other countries and practices in China. Results and
    Conclusion Comprehensive intervention of hospitals and communities as well as the policy system of basic health care insurance and
    social assistance can significantly reduce the economic burden of the schizophrenia.
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    Patent Status of Antidepressants: Duloxetine
    LI Jun-li;WEN Qi;YU Pei-ming
    2014 (2):  87-91.  doi:
    摘要 ( 519 )  
    Objective To study the patent status of duloxetine and to provide references for the strategic development of pharmaceutical
    companies in China. Methods Patent status of duloxetine in China were analyzed by quantitative and qualitative methods of research.
    Results and Conclusion Generic manufacturers can produce duloxetine legally when the administrative protection ends on December
    11, 2013. But crystal and process patents should be paid attention to avoid infringement. The generic manufacturers can analyze
    the patents of synthesis process and pharmaceutical formulations, to obtain the best processing route to reduce production cost or to
    apply for patents on their own. There is still great potential for pharmaceutical companies in China to make new breakthroughs by
    absorbing technology in previous patents.
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    Study on the Pharmaceutical E-commerce B to C Modelfrom Perspective of Transaction Costs
    ZHANG Lei;XING Hua;WU Yang
    2014 (2):  92-95.  doi:
    摘要 ( 535 )  
    Objective To probe into the reasons why pharmaceutical E-commerce develops slowly and to promote the E-commerce applications
    to pharmaceutical retail industry. Methods Pharmaceutical e-commerce and traditional retail models were compared, and some
    suggestions were raised from the perspective of transaction costs. Results and Conclusion At present, transaction costs of the
    emerging pharmaceutical E-commerce B to C model have not been reduced much compared with the traditional retail model,
    that is, E-commerce B to C model has not gained a significant advantage. Therefore, government, enterprises and other parties
    should cooperate to cut down the transaction costs of drugs via the Internet so as to promote the E-commerce applications to the
    pharmaceutical retail industry.
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